The story began in 1994 when the Multidisciplinary Association for Psychedelic Studies (MAPS) introduced Dr. Kolp to Dr. Evgeny Krupitsky, a Soviet researcher specializing in ketamine psychedelic psychotherapy. Inspired by the scientific work of Dr. Krupitsky, who conducted the most comprehensive and rigorous clinical research on ketamine-assisted psychotherapy to date, Dr. Kolp first discovered the potential of ketamine as an adjunct to psychotherapy in 1994. In 1995, he developed a research protocol, entitled Ketamine-Assisted Therapy of Alcoholism. The protocol was reviewed and approved by the James A. Haley Veterans Hospital , the University of South Florida College of Medicine , and the U.S. Food and Drug Administration (FDA) . After receiving an Investigational New Drug permit in 1996, Dr. Kolp became engaged in research into the effectiveness of ketamine-assisted therapy for the treatment of alcoholism. Please visit our Resources page to view the original documents and learn more.

After collecting preliminary data and gaining experience administering ketamine-assisted therapy, Dr. Kolp began using ketamine-assisted psychotherapy for clinical applications in his private practice. In 2003, he founded the not-for-profit foundation Eleusis to utilize what he called “ketamine-enhanced psychotherapy” (KEP) to treat his alcoholic clients. His approach was explicitly designed to replicate Krupitsky’s pioneering work and apply it in a new cultural context: the United States. Like Krupitsky’s technique, Dr. Kolp’s KEP relies on a ketamine-induced transpersonal experience to facilitate psychotherapeutic changes.

Dr. Kolp initially used KEP as a component of individual psychotherapy programs administered on an outpatient basis. He later discovered that KEP is more effective as an adjunct to group psychotherapy, administered in the context of a structured residential program.

In addition to KEP, the Wellness Enhancement and Longevity Learning (WELL) Program at Eleusis incorporated existential and transpersonal group psychotherapies, as well as several various alternative therapeutic techniques including meditation, guided imagery, visualization, Holotropic Breathwork, yoga, and Wisdom Circle groups. The three-week WELL program offered more than 90 hours of encounter groups, interactive classes, and didactic lectures in a structured residential setting.

During the same period of time, Dr. Kolp administered KEP for people suffering from death anxiety during the end stage of terminal cancer. Dr. Kolp offered KEP to hospice clients to help them resolve their fears when confronting death. KEP, combined with existential and transpersonal psychotherapy, was administered to dying patients as part of an intensive, individual outpatient treatment consisting of five 75 to 80-minute sessions.

Dr. Kolp found that two-thirds of his alcoholic patients responded well to KEP, and many recovered from their addiction. Many of his patients also showed significant or moderate improvement in their co-existing psychological and psychosomatic illnesses, such as generalized anxiety disorder, social phobias, primary insomnia, acute and repeated stress disorder, pain disorder, tension and migraine headaches, somatization disorder, and chronic fatigue syndrome.

Building on this extensive experience, Dr. Kolp resolved to follow a common wisdom — “An ounce of prevention is better than a pound of cure” — and changed his approach from treatment-oriented to growth-oriented or preventive medicine. Utilizing the same techniques offered at Eleusis, the WELL Program offered through The Kolp Institute is a seven day program specifically aimed for successful professionals, business people, and others interested in a transformational experience, with little time, suffering from stress, burnout, and fatigue as the result of their demanding lives. Beginning with six weeks of at-home detoxification and preparation, culminating in the one-week WELL Program workshop, clients center their focus on personal growth and work to shed the common lifestyle addictions to salt, milk fat, refined sugars, animal protein and lards, caffeine, nicotine, and alcohol, as well as every day dependencies on various over the counter and prescription medications.